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Discovery
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Discovery
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Process R&D
Process R&D
Technology and Platforms
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COVID-19 Statement
SpiroTeam
New Products & Concept
Events, conferences and webinars
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Reach the Summit
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New Products & Concept

Mar 24, 2017

SpiroChem strengthens its Management Team!...

SpiroTeam

Feb 10, 2017

SpiroChem welcomes a New Member...

SpiroTeam

Jan 30, 2017

The SpiroChem team is glad...

Conferences, Events, conferences and webinars, SpiroTeam

Nov 12, 2016

SpiroChem is glad to welcome...

Conferences, Events, conferences and webinars, SpiroTeam

Sep 06, 2016

SpiroChem team is back from...

Press Releases

May 30, 2016

Interview of Thomas C. Fessard...

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Discovery
Process R&D
Technology and Platforms
Compound Collections
News
Careers
About

Get in touch

contact@spirochem.com +41 61 685 9500 Follow us

Informations

Terms & Conditions

Impressum

https://tools.google.com/dlpage/gaoptout
https://allaboutcookies.org/

Stay Connected

Stay inspired with our newsletter subscription, keeping you informed on new concepts, products, solutions & more.

Medicinal Chemistry

Our Mission: Accelerate your project!

Typically : 1-6 chemists

Duration : 3-12+ months

Excellence in chemistry
Creative drug design
Solution and productivity driven
Uncompromised quality

Full MedChem programs or Support for a specific phase:

Hit Validation
Hit/Fragment Expansion
Hit-to-Lead

Lead Optimization
SAR Elucidation
Bioisosteric replacement strategies

Properties Optimization
Back-up programs
IP Evaluation
Patent Filing

Hit Validation
Hit/Fragment Expansion
Hit-to-Lead
Lead Optimization
SAR Elucidation

Bioisosteric replacement strategies
Properties Optimization
Back-up programs
IP Evaluation
Patent Filing

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MedChem Enabling Platforms

Our Mission: Explore new chemical space for you

Typically : 2-5 chemists

Duration : 3-12+ months

Opening of new exit vectors
Late-stage functionalization
Synthesis tractability
Unleashed design

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Fragment Libraries

Our Mission: Address unexplored chemical space and diversity

+700 molecules in stock
Unique design
High sp³ content
Conformationally restricted structures
Scale-up and straightforward analoging guaranteed

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DEL Scaffolds

Our Mission : Offer exclusive scaffolds

Bi- and tri-functionalized scaffolds
Uncharted chemical space
Unique dihedral angles covered
Orthogonal protecting groups
Vectors : COOH, CHO, Aryl halides, Nboc, Nfmoc, boronates

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Route Scouting

Our Mission: Design and implement de novo synthetic routes

Typically: 1-3 chemists

Duration: 3-6+ months

De novo design of synthetic routes to target molecules
Trouble-shooting
Development of efficient in-process controls
Stress test, robustness check
Technology transfer package

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SpiroKits

The must-have medicinal chemistry toolbox designed to:

Provide medchem turnkey solutions
Accelerate projects
Foster chemical space exploration
Support novelty

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Catalog

Our mission: Accelerate your R&D

+13 000 molecules
Innovative building blocks
Purity > 95%
Milligram to hundred gram scale
Short delivery time

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Consulting

Our mission: Share our knowledge

Literature analysis
Analysis of SAR results and proposals
Strategy proposals for ADME optimization
Retrosynthetic analysis
Route scouting proposals
Patent gap analysis
Support for patent filing

*hourly rate, daily rate or project-based fee

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Computational Chemistry

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SpiroSpace

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Press Releases

SpiroCycles – Episode 1/2.

SpiroChem strengthens its Management Team!...

SpiroChem welcomes a New Member...

New team member | SpiroChem.

The SpiroChem team is glad...

SpiroChem team - in France...

SpiroChem is glad to welcome...

SpiroChem team is back from...

Interview of Thomas C. Fessard...

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