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SpiroChem’s High Throughput Experimention Platform is an integrated and fully automated system engineered to rapidly design, execute, and analyze dozens to hundreds experiments in parallel. By combining automation, advanced instrumentation, and data-driven analysis, the platform enables rapid screening of key parameters such as reagents, bases, catalysts and ligands, simultaneously rather than sequentially. This cost-effective approach supports fast decision-making by accelerating the identification of optimal reaction conditions from early-phase discovery through process development.
At any project stage, our experts will tailor a streamlined experimental strategy to quickly identify robust and scalable conditions for your transformation.
Automated sample preparation, robotic liquid and solid handling, and fully integrated LC-MS and SFC analytics eliminate manual handoffs and delays, ensuring fast, reliable results and continuous data flow. From plate design to analytical reporting, our integrated system processes experiments across 24- to 384-well formats with a fast turnaround, typically delivering plate-to-report results within 2–3 days for a 96-well plate.
Our HTE infrastructure is engineered to support the demanding conditions often required in modern chemical discovery and process optimization.
Advanced capabilities include:
For air-sensitive chemistry
Up to 200 °C / 100 bar
and down to -50 °C
Large panel of enzymes available
This robust setup allows exploration of complex chemical spaces efficiently while maintaining reproducibility and data quality.
Our platform supports a wide range of reaction classes used in both discovery and process chemistry, including:
Pd, Pt, Rh, Ru
To maximize the impact of every screening campaign, SpiroChem collaborates with a network of specialized partners. This ecosystem allows rapid access and evaluation of diverse catalytic systems and reagents, expanding the chemical space available to our clients.
Through these partnerships we can source and screen:
This collaborative network ensures that each HTE campaign can leverage the best available catalysts and technologies, accelerating optimization and increasing the rate of success.
